How do microorganisms "talk" to human cells and benefit our health? I am interested in investigating the molecular mechanisms governing trans-kingdom signaling and its impact on human health. Understanding microbe-host communication at both cellular and molecular levels will advance our knowledge on how microbial signals influence the biological progression of diseases, including cancer, immune, metabolic and neurological disorders. It will also shed light on disease prevention and treatment.
During my Ph.D. study in Dr. Meng Wang's laboratory at Baylor College of Medicine, I used Caenorhabditis elegans as a model system to explore the mechanism by which environmental variation tunes the dynamics of cross-species interactions. By harnessing the power of chemical imaging, metabolomics, transcriptome, functional genomics, and bioinformatics, I discovered a novel microbe-host chemical communication in regulating lipid metabolism. Furthermore, my work revealed the exciting role of mitochondrial dynamics in mediating microbe-host interactions.
Following my passion for microbe-host interaction, I am currently a postdoctoral fellow in Dr. Andrew Clark's laboratory in the Department of Molecular Biology and Genetics at Cornell University. I will investigate how microbes impact our health by using the fruit fly Drosophila melanogaster as a model system.
Post-Doctoral Fellowship at Cornell University Present - Ithaca, NY, USA. Ph.D. from Baylor College of Medicine 2017 - Houston, TX, USA. B.S. from National Taiwan University 2010 - Taipei, Taiwan.