POSTDOCTORAL RESEARCH
2018-present
Postdoctoral Fellow
(1) Investigating the function of beneficial prion proteins in the mycobiome.
(2) Uncovering mycobiome genetic composition that promotes host health and fitness.
Advisor: Andrew G. Clark, Ph.D., Cornell University, Ithaca, NY, USA.
Postdoctoral Fellow
(1) Investigating the function of beneficial prion proteins in the mycobiome.
(2) Uncovering mycobiome genetic composition that promotes host health and fitness.
Advisor: Andrew G. Clark, Ph.D., Cornell University, Ithaca, NY, USA.
2017-2018
Transitory Postdoctoral Position
Studied the molecular basis of longevity by chemical biology approaches.
Advisor: Meng C. Wang, Ph.D., Baylor College of Medicine, Houston, TX, USA.
Transitory Postdoctoral Position
Studied the molecular basis of longevity by chemical biology approaches.
Advisor: Meng C. Wang, Ph.D., Baylor College of Medicine, Houston, TX, USA.
GRADUATE RESEARCH
2011-2017
Ph.D. Thesis Research
(1) Discovered a novel microbe-host chemical communication in regulating lipid metabolism, and delineated the complete signaling cascade in this regulation.
(2) Investigated roles of host mitochondria in microbiota-induced longevity.
(3) Developed a new chemical imaging technology by which small molecules can be visualized in live cells using alkyne-tag stimulated Raman scattering microscopy.
(4) Elucidated functions of the LRH-1 receptor in regulating mitochondrial dynamics in mammalian systems.
(5) Designed and performed a chemical mutagenesis screen to identify genes that regulate mitochondrial unfolded protein response.
Advisor: Meng C. Wang, Ph.D., Baylor College of Medicine, Houston, TX, USA.
Ph.D. Thesis Research
(1) Discovered a novel microbe-host chemical communication in regulating lipid metabolism, and delineated the complete signaling cascade in this regulation.
(2) Investigated roles of host mitochondria in microbiota-induced longevity.
(3) Developed a new chemical imaging technology by which small molecules can be visualized in live cells using alkyne-tag stimulated Raman scattering microscopy.
(4) Elucidated functions of the LRH-1 receptor in regulating mitochondrial dynamics in mammalian systems.
(5) Designed and performed a chemical mutagenesis screen to identify genes that regulate mitochondrial unfolded protein response.
Advisor: Meng C. Wang, Ph.D., Baylor College of Medicine, Houston, TX, USA.
2010-2011
Ph.D. Rotation Research
Applied synthetic biology approach to develop biosensors for detections of Gram type-specific bacteria in amoeba cells.
Advisor: Adam Kuspa, Ph.D., Baylor College of Medicine, Houston, TX, USA.
Established RNAi-based genetic screens for oxidative stress resistance and germline tumor protection in the nematode.
Advisor: Meng Wang, Ph.D., Baylor College of Medicine, Houston, TX, USA.
Investigated Potocki-Lupski syndrome & Smith-Magenis syndrome by a two-hybrid screening of RAI1 interacting targets in mice.
Advisor: James Lupski, M.D., Ph.D., Baylor College of Medicine, Houston, TX, USA.
Studied the regulation of chromosome recombination by epigenetic modulation in yeast.
Advisor: Gregory Ira, Ph.D., Baylor College of Medicine, Houston, TX, USA.
Performed data mining for causative mutations from the variant output of whole-exome sequencing in patients with trigeminal neuralgia.
Advisor: Penelope Bonnen, Ph.D., Baylor College of Medicine, Houston, TX, USA.
Ph.D. Rotation Research
Applied synthetic biology approach to develop biosensors for detections of Gram type-specific bacteria in amoeba cells.
Advisor: Adam Kuspa, Ph.D., Baylor College of Medicine, Houston, TX, USA.
Established RNAi-based genetic screens for oxidative stress resistance and germline tumor protection in the nematode.
Advisor: Meng Wang, Ph.D., Baylor College of Medicine, Houston, TX, USA.
Investigated Potocki-Lupski syndrome & Smith-Magenis syndrome by a two-hybrid screening of RAI1 interacting targets in mice.
Advisor: James Lupski, M.D., Ph.D., Baylor College of Medicine, Houston, TX, USA.
Studied the regulation of chromosome recombination by epigenetic modulation in yeast.
Advisor: Gregory Ira, Ph.D., Baylor College of Medicine, Houston, TX, USA.
Performed data mining for causative mutations from the variant output of whole-exome sequencing in patients with trigeminal neuralgia.
Advisor: Penelope Bonnen, Ph.D., Baylor College of Medicine, Houston, TX, USA.
UNDERGRAD RESEARCH
2008
Summer Research Scholar
Characterized the extracellular matrix remolding triggered by inflammatory factors in primary adipose tissue.
Advisor: Kola Ajuwon, Ph.D., Purdue University, West Lafayette, IN, USA.
2007-2009
Undergrad Independent Study
(1) Characterized the expression and functions of the reproductive regulator Kisspeptin in avian and mammalian models.
(2) Investigated mitochondrial biogenesis induced by ox-LDL in RAW264.7 macrophage cell line.
Advisors: Chih-Hsien Chiu, Ph.D. and De-Shien Jong, Ph.D., National Taiwan University, Taipei, Taiwan.
Summer Research Scholar
Characterized the extracellular matrix remolding triggered by inflammatory factors in primary adipose tissue.
Advisor: Kola Ajuwon, Ph.D., Purdue University, West Lafayette, IN, USA.
2007-2009
Undergrad Independent Study
(1) Characterized the expression and functions of the reproductive regulator Kisspeptin in avian and mammalian models.
(2) Investigated mitochondrial biogenesis induced by ox-LDL in RAW264.7 macrophage cell line.
Advisors: Chih-Hsien Chiu, Ph.D. and De-Shien Jong, Ph.D., National Taiwan University, Taipei, Taiwan.
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